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simaerep

Detect Clinical Trial Sites Over- or Under-Reporting Clinical Events

Monitoring reporting rates of subject-level clinical events (e.g. adverse events, protocol deviations) reported by clinical trial sites is an important aspect of risk-based quality monitoring strategy. Sites that are under-reporting or over-reporting events can be detected using bootstrap simulations during which patients are redistributed between sites. Site-specific distributions of event reporting rates are generated that are used to assign probabilities to the observed reporting rates. (Koneswarakantha 2024 <doi:10.1007/s43441-024-00631-8>).

Versions across snapshots

VersionRepositoryFileSize
1.0.0 rolling linux/jammy R-4.5 simaerep_1.0.0.tar.gz 626.5 KiB
1.0.0 rolling linux/noble R-4.5 simaerep_1.0.0.tar.gz 626.9 KiB
1.0.0 rolling source/ R- simaerep_1.0.0.tar.gz 560.5 KiB
1.0.0 latest linux/jammy R-4.5 simaerep_1.0.0.tar.gz 626.5 KiB
1.0.0 latest linux/noble R-4.5 simaerep_1.0.0.tar.gz 626.9 KiB
1.0.0 latest source/ R- simaerep_1.0.0.tar.gz 560.5 KiB
1.0.0 2026-04-26 source/ R- simaerep_1.0.0.tar.gz 560.5 KiB
1.0.0 2026-04-23 source/ R- simaerep_1.0.0.tar.gz 560.5 KiB
1.0.0 2026-04-09 windows/windows R-4.5 simaerep_1.0.0.zip 632.7 KiB
0.7.0 2025-04-20 source/ R- simaerep_0.7.0.tar.gz 629.1 KiB

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