twoCoprimary
Sample Size and Power Calculation for Two Co-Primary Endpoints
Comprehensive functions to calculate sample size and power for clinical trials with two co-primary endpoints. The package supports five endpoint combinations: two continuous endpoints (Sozu et al. 2011 <doi:10.1080/10543406.2011.551329>), two binary endpoints using asymptotic methods (Sozu et al. 2010 <doi:10.1002/sim.3972>) and exact methods (Homma and Yoshida 2025 <doi:10.1177/09622802251368697>), mixed continuous and binary endpoints (Sozu et al. 2012 <doi:10.1002/bimj.201100221>), and mixed count and continuous endpoints (Homma and Yoshida 2024 <doi:10.1002/pst.2337>). All methods appropriately account for correlation between endpoints and provide both sample size and power calculation capabilities.
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
1.0.0 |
rolling linux/jammy R-4.5 | twoCoprimary_1.0.0.tar.gz |
340.3 KiB |
1.0.0 |
rolling linux/noble R-4.5 | twoCoprimary_1.0.0.tar.gz |
340.4 KiB |
1.0.0 |
rolling source/ R- | twoCoprimary_1.0.0.tar.gz |
220.8 KiB |
1.0.0 |
latest linux/jammy R-4.5 | twoCoprimary_1.0.0.tar.gz |
340.3 KiB |
1.0.0 |
latest linux/noble R-4.5 | twoCoprimary_1.0.0.tar.gz |
340.4 KiB |
1.0.0 |
latest source/ R- | twoCoprimary_1.0.0.tar.gz |
220.8 KiB |
1.0.0 |
2026-04-26 source/ R- | twoCoprimary_1.0.0.tar.gz |
220.8 KiB |
1.0.0 |
2026-04-23 source/ R- | twoCoprimary_1.0.0.tar.gz |
220.8 KiB |
1.0.0 |
2026-04-09 windows/windows R-4.5 | twoCoprimary_1.0.0.zip |
360.6 KiB |