Crandore Hub

idiffomix

Integrated Differential Analysis of Multi Omics Data using a Joint Mixture Model

A joint mixture model has been developed by Majumdar et al. (2025) <doi:10.48550/arXiv.2412.17511> that integrates information from gene expression data and methylation data at the modelling stage to capture their inherent dependency structure, enabling simultaneous identification of differentially methylated cytosine-guanine dinucleotide (CpG) sites and differentially expressed genes. The model leverages a joint likelihood function that accounts for the nested structure in the data, with parameter estimation performed using an expectation-maximisation algorithm.

Versions across snapshots

VersionRepositoryFileSize
1.0.0 rolling linux/jammy R-4.5 idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 rolling linux/noble R-4.5 idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 rolling source/ R- idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 latest linux/jammy R-4.5 idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 latest linux/noble R-4.5 idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 latest source/ R- idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 2026-04-26 source/ R- idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 2026-04-23 source/ R- idiffomix_1.0.0.tar.gz 94.6 KiB
1.0.0 2025-04-20 source/ R- idiffomix_1.0.0.tar.gz 94.6 KiB

Dependencies (latest)

Imports

Suggests