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grantham

Calculate the Grantham Distance

A minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Versions across snapshots

VersionRepositoryFileSize
0.1.4 rolling linux/jammy R-4.5 grantham_0.1.4.tar.gz 224.0 KiB
0.1.4 rolling linux/noble R-4.5 grantham_0.1.4.tar.gz 223.8 KiB
0.1.4 rolling source/ R- grantham_0.1.4.tar.gz 194.1 KiB
0.1.4 latest linux/jammy R-4.5 grantham_0.1.4.tar.gz 224.0 KiB
0.1.4 latest linux/noble R-4.5 grantham_0.1.4.tar.gz 223.8 KiB
0.1.4 latest source/ R- grantham_0.1.4.tar.gz 194.1 KiB
0.1.4 2026-04-26 source/ R- grantham_0.1.4.tar.gz 194.1 KiB
0.1.4 2026-04-23 source/ R- grantham_0.1.4.tar.gz 194.1 KiB
0.1.4 2026-04-09 windows/windows R-4.5 grantham_0.1.4.zip 227.6 KiB
0.1.2 2025-04-20 source/ R- grantham_0.1.2.tar.gz 193.8 KiB

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