grantham
Calculate the Grantham Distance
A minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
0.1.4 |
2026-04-09 windows/windows R-4.5 | grantham_0.1.4.zip |
227.6 KiB |