SimDissolution
Modeling and Assessing Similarity of Drug Dissolutions Profiles
Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) <doi:10.1002/sim.7689> for details.
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
0.1.0 |
rolling linux/jammy R-4.5 | SimDissolution_0.1.0.tar.gz |
38.2 KiB |
0.1.0 |
rolling linux/noble R-4.5 | SimDissolution_0.1.0.tar.gz |
38.2 KiB |
0.1.0 |
rolling source/ R- | SimDissolution_0.1.0.tar.gz |
6.7 KiB |
0.1.0 |
latest linux/jammy R-4.5 | SimDissolution_0.1.0.tar.gz |
38.2 KiB |
0.1.0 |
latest linux/noble R-4.5 | SimDissolution_0.1.0.tar.gz |
38.2 KiB |
0.1.0 |
latest source/ R- | SimDissolution_0.1.0.tar.gz |
6.7 KiB |
0.1.0 |
2026-04-26 source/ R- | SimDissolution_0.1.0.tar.gz |
6.7 KiB |
0.1.0 |
2026-04-23 source/ R- | SimDissolution_0.1.0.tar.gz |
6.7 KiB |
0.1.0 |
2026-04-09 windows/windows R-4.5 | SimDissolution_0.1.0.zip |
41.9 KiB |
0.1.0 |
2025-04-20 source/ R- | SimDissolution_0.1.0.tar.gz |
6.7 KiB |