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MiRKAT

Microbiome Regression-Based Kernel Association Tests

Test for overall association between microbiome composition data and phenotypes via phylogenetic kernels. The phenotype can be univariate continuous or binary (Zhao et al. (2015) <doi:10.1016/j.ajhg.2015.04.003>), survival outcomes (Plantinga et al. (2017) <doi:10.1186/s40168-017-0239-9>), multivariate (Zhan et al. (2017) <doi:10.1002/gepi.22030>) and structured phenotypes (Zhan et al. (2017) <doi:10.1111/biom.12684>). The package can also use robust regression (unpublished work) and integrated quantile regression (Wang et al. (2021) <doi:10.1093/bioinformatics/btab668>). In each case, the microbiome community effect is modeled nonparametrically through a kernel function, which can incorporate phylogenetic tree information.

Versions across snapshots

VersionRepositoryFileSize
1.2.3 rolling linux/jammy R-4.5 MiRKAT_1.2.3.tar.gz 362.4 KiB
1.2.3 rolling linux/noble R-4.5 MiRKAT_1.2.3.tar.gz 362.5 KiB
1.2.3 rolling source/ R- MiRKAT_1.2.3.tar.gz 234.5 KiB
1.2.3 latest linux/jammy R-4.5 MiRKAT_1.2.3.tar.gz 362.4 KiB
1.2.3 latest linux/noble R-4.5 MiRKAT_1.2.3.tar.gz 362.5 KiB
1.2.3 latest source/ R- MiRKAT_1.2.3.tar.gz 234.5 KiB
1.2.3 2026-04-26 source/ R- MiRKAT_1.2.3.tar.gz 234.5 KiB
1.2.3 2026-04-23 source/ R- MiRKAT_1.2.3.tar.gz 234.5 KiB
1.2.3 2026-04-09 windows/windows R-4.5 MiRKAT_1.2.3.zip 365.8 KiB
1.2.3 2025-04-20 source/ R- MiRKAT_1.2.3.tar.gz 234.5 KiB

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