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GUniFrac

Generalized UniFrac Distances, Distance-Based Multivariate Methods and Feature-Based Univariate Methods for Microbiome Data Analysis

A suite of methods for powerful and robust microbiome data analysis including data normalization, data simulation, community-level association testing and differential abundance analysis. It implements generalized UniFrac distances, Geometric Mean of Pairwise Ratios (GMPR) normalization, semiparametric data simulator, distance-based statistical methods, and feature-based statistical methods. The distance-based statistical methods include three extensions of PERMANOVA: (1) PERMANOVA using the Freedman-Lane permutation scheme, (2) PERMANOVA omnibus test using multiple matrices, and (3) analytical approach to approximating PERMANOVA p-value. Feature-based statistical methods include linear model-based methods for differential abundance analysis of zero-inflated high-dimensional compositional data.

Versions across snapshots

VersionRepositoryFileSize
1.9 rolling source/ R- GUniFrac_1.9.tar.gz 821.3 KiB
1.9 rolling linux/jammy R-4.5 GUniFrac_1.9.tar.gz 1014.0 KiB
1.9 rolling linux/noble R-4.5 GUniFrac_1.9.tar.gz 1015.5 KiB
1.9 latest source/ R- GUniFrac_1.9.tar.gz 821.3 KiB
1.9 latest linux/jammy R-4.5 GUniFrac_1.9.tar.gz 1014.0 KiB
1.9 latest linux/noble R-4.5 GUniFrac_1.9.tar.gz 1015.5 KiB
1.9 2026-04-23 source/ R- GUniFrac_1.9.tar.gz 821.3 KiB
1.9 2026-04-09 windows/windows R-4.5 GUniFrac_1.9.zip 1.3 MiB
1.8 2025-04-20 source/ R- GUniFrac_1.8.tar.gz 851.7 KiB

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