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HACSim

Iterative Extrapolation of Species' Haplotype Accumulation Curves for Genetic Diversity Assessment

Performs iterative extrapolation of species' haplotype accumulation curves using a nonparametric stochastic (Monte Carlo) optimization method for assessment of specimen sampling completeness based on the approach of Phillips et al. (2015) <doi:10.1515/dna-2015-0008>, Phillips et al. (2019) <doi:10.1002/ece3.4757> and Phillips et al. (2020) <doi: 10.7717/peerj-cs.243>. 'HACSim' outputs a number of useful summary statistics of sampling coverage ("Measures of Sampling Closeness"), including an estimate of the likely required sample size (along with desired level confidence intervals) necessary to recover a given number/proportion of observed unique species' haplotypes. Any genomic marker can be targeted to assess likely required specimen sample sizes for genetic diversity assessment. The method is particularly well-suited to assess sampling sufficiency for DNA barcoding initiatives. Users can also simulate their own DNA sequences according to various models of nucleotide substitution. A Shiny app is also available.

Versions across snapshots

VersionRepositoryFileSize
1.0.7-1 rolling source/ R- HACSim_1.0.7-1.tar.gz 23.7 KiB
1.0.7-1 rolling linux/jammy R-4.5 HACSim_1.0.7-1.tar.gz 105.0 KiB
1.0.7-1 rolling linux/noble R-4.5 HACSim_1.0.7-1.tar.gz 106.9 KiB
1.0.7-1 latest source/ R- HACSim_1.0.7-1.tar.gz 23.7 KiB
1.0.7-1 latest linux/jammy R-4.5 HACSim_1.0.7-1.tar.gz 105.0 KiB
1.0.7-1 latest linux/noble R-4.5 HACSim_1.0.7-1.tar.gz 106.9 KiB
1.0.7-1 2026-04-23 source/ R- HACSim_1.0.7-1.tar.gz 23.7 KiB
1.0.7-1 2026-04-09 windows/windows R-4.5 HACSim_1.0.7-1.zip 427.4 KiB
1.0.6-1 2025-04-20 source/ R- HACSim_1.0.6-1.tar.gz 4.1 MiB

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