CytoProfile
Cytokine Profiling Analysis Tool
Provides comprehensive cytokine profiling analysis through quality control using biologically meaningful cutoffs on raw cytokine measurements and by testing for distributional symmetry to recommend appropriate transformations. Offers exploratory data analysis with summary statistics, enhanced boxplots, and barplots, along with univariate and multivariate analytical capabilities for in-depth cytokine profiling such as Principal Component Analysis based on Andrzej Maćkiewicz and Waldemar Ratajczak (1993) <doi:10.1016/0098-3004(93)90090-R>, Sparse Partial Least Squares Discriminant Analysis based on Lê Cao K-A, Boitard S, and Besse P (2011) <doi:10.1186/1471-2105-12-253>, Random Forest based on Breiman, L. (2001) <doi:10.1023/A:1010933404324>, and Extreme Gradient Boosting based on Tianqi Chen and Carlos Guestrin (2016) <doi:10.1145/2939672.2939785>.
README
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# CytoProfile <a href="https://cytoprofile.cytokineprofile.org/"><img src="man/figures/logo.png" align="right" height="133" alt="CytoProfile website" /></a>
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**CRAN Build Status:** [](https://github.com/saraswatsh/CytoProfile/actions/workflows/R-CMD-check.yaml)
[](https://CRAN.R-project.org/package=CytoProfile)
[](https://cran.r-project.org/web/checks/check_results_CytoProfile.html)
[](https://cran.r-project.org/package=CytoProfile)
[](https://github.com/saraswatsh/CytoProfile/commits/main/)
**Development Build Status:** [](https://github.com/saraswatsh/CytoProfile/actions/workflows/R-CMD-check.yaml)
[](https://github.com/saraswatsh/CytoProfile/tree/devel)
[](https://github.com/saraswatsh/CytoProfile/commits/devel/)
[](https://www.codefactor.io/repository/github/saraswatsh/cytoprofile/overview/devel)
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The goal of CytoProfile is to conduct quality control using biological
meaningful cutoff on raw measured values of cytokines. Specifically,
test on distributional symmetry to suggest the adopt of transformation.
Conduct exploratory analysis including summary statistics, generate
enriched barplots, and boxplots. Further, conduct univariate analysis
and multivariate analysis for advance analysis.
## Installation
Before installation of the CytoProfile package, make sure to install
BiocManager and mixOmics packages using:
``` r
## install BiocManager
if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager")
## install mixOmics
BiocManager::install('mixOmics')
```
You can install the development version of CytoProfile from
[GitHub](https://github.com/saraswatsh/CytoProfile/tree/devel) with:
``` r
# install.packages("devtools")
devtools::install_github("saraswatsh/CytoProfile", ref = "devel")
```
Install CytoProfile from
[CRAN](https://cran.r-project.org/package=CytoProfile) with:
``` r
install.packages("CytoProfile")
```
See change log for the latest updates and changes on release build at
[News](https://cytoprofile.cytokineprofile.org/news/index.html) and
development build at
[News](https://cytoprofile.cytokineprofile.org/dev/news/index.html).
To look at the vignettes included in the package, use:
``` r
browseVignettes("CytoProfile")
```
[Vignettes](https://cytoprofile.cytokineprofile.org//dev/articles/index.html)
are also available on CytoProfile website to learn how to use the
package.
For more details on the released build of the package, please visit the
[CytoProfile website](https://cytoprofile.cytokineprofile.org/). For the
development version of the package, please visit the [Development
CytoProfile website](https://cytoprofile.cytokineprofile.org/dev/).
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
0.2.4 |
rolling linux/jammy R-4.5 | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.4 |
rolling linux/noble R-4.5 | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.4 |
rolling source/ R- | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.4 |
latest linux/jammy R-4.5 | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.4 |
latest linux/noble R-4.5 | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.4 |
latest source/ R- | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.4 |
2026-04-26 source/ R- | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.4 |
2026-04-23 source/ R- | CytoProfile_0.2.4.tar.gz |
939.7 KiB |
0.2.0 |
2025-04-20 source/ R- | CytoProfile_0.2.0.tar.gz |
414.0 KiB |