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upndown

Utilities and Design Aids for Up-and-Down Dose-Finding Studies

Up-and-Down (UD) is the most popular design approach for dose-finding, but it has been severely under-served by the statistical and computing communities. This is the first package that comprehensively addresses UD's needs. Recent applied UD tutorial: Oron et al., 2022 <doi:10.1097/ALN.0000000000004282>. Recent methodological overview: Oron and Flournoy, 2024 <doi:10.51387/24-NEJSDS74>.

Versions across snapshots

VersionRepositoryFileSize
0.3.0 rolling linux/jammy R-4.5 upndown_0.3.0.tar.gz 249.2 KiB
0.3.0 rolling linux/noble R-4.5 upndown_0.3.0.tar.gz 249.2 KiB
0.3.0 rolling source/ R- upndown_0.3.0.tar.gz 142.5 KiB
0.3.0 latest linux/jammy R-4.5 upndown_0.3.0.tar.gz 249.2 KiB
0.3.0 latest linux/noble R-4.5 upndown_0.3.0.tar.gz 249.2 KiB
0.3.0 latest source/ R- upndown_0.3.0.tar.gz 142.5 KiB
0.3.0 2026-04-26 source/ R- upndown_0.3.0.tar.gz 142.5 KiB
0.3.0 2026-04-23 source/ R- upndown_0.3.0.tar.gz 142.5 KiB
0.3.0 2026-04-09 windows/windows R-4.5 upndown_0.3.0.zip 252.1 KiB
0.2.0 2025-04-20 source/ R- upndown_0.2.0.tar.gz 139.5 KiB

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