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titeIR

Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities

Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.

Versions across snapshots

VersionRepositoryFileSize
0.1.0 rolling linux/jammy R-4.5 titeIR_0.1.0.tar.gz 25.2 KiB
0.1.0 rolling linux/noble R-4.5 titeIR_0.1.0.tar.gz 25.2 KiB
0.1.0 rolling source/ R- titeIR_0.1.0.tar.gz 4.5 KiB
0.1.0 latest linux/jammy R-4.5 titeIR_0.1.0.tar.gz 25.2 KiB
0.1.0 latest linux/noble R-4.5 titeIR_0.1.0.tar.gz 25.2 KiB
0.1.0 latest source/ R- titeIR_0.1.0.tar.gz 4.5 KiB
0.1.0 2026-04-26 source/ R- titeIR_0.1.0.tar.gz 4.5 KiB
0.1.0 2026-04-23 source/ R- titeIR_0.1.0.tar.gz 4.5 KiB
0.1.0 2026-04-09 windows/windows R-4.5 titeIR_0.1.0.zip 27.7 KiB
0.1.0 2025-04-20 source/ R- titeIR_0.1.0.tar.gz 4.5 KiB

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Imports