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simIDM

Simulating Oncology Trials using an Illness-Death Model

Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.

Versions across snapshots

VersionRepositoryFileSize
0.1.0 rolling linux/jammy R-4.5 simIDM_0.1.0.tar.gz 805.1 KiB
0.1.0 rolling linux/noble R-4.5 simIDM_0.1.0.tar.gz 804.8 KiB
0.1.0 rolling source/ R- simIDM_0.1.0.tar.gz 778.8 KiB
0.1.0 latest linux/jammy R-4.5 simIDM_0.1.0.tar.gz 805.1 KiB
0.1.0 latest linux/noble R-4.5 simIDM_0.1.0.tar.gz 804.8 KiB
0.1.0 latest source/ R- simIDM_0.1.0.tar.gz 778.8 KiB
0.1.0 2026-04-26 source/ R- simIDM_0.1.0.tar.gz 778.8 KiB
0.1.0 2026-04-23 source/ R- simIDM_0.1.0.tar.gz 778.8 KiB
0.1.0 2026-04-09 windows/windows R-4.5 simIDM_0.1.0.zip 818.2 KiB
0.1.0 2025-04-20 source/ R- simIDM_0.1.0.tar.gz 778.8 KiB

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