segregatr
Segregation Analysis for Variant Interpretation
An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>. This implementation supports custom penetrance values and liability classes, and allows visualisations and robustness analysis as presented in Ratajska et al. (2023) <doi:10.1002/mgg3.2107>. See also the online app 'shinyseg', <https://chrcarrizosa.shinyapps.io/shinyseg>, which offers interactive segregation analysis with many additional features (Carrizosa et al. (2024) <doi:10.1093/bioinformatics/btae201>).
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
0.5.0 |
rolling linux/jammy R-4.5 | segregatr_0.5.0.tar.gz |
64.3 KiB |
0.5.0 |
rolling linux/noble R-4.5 | segregatr_0.5.0.tar.gz |
64.2 KiB |
0.5.0 |
rolling source/ R- | segregatr_0.5.0.tar.gz |
31.2 KiB |
0.5.0 |
latest linux/jammy R-4.5 | segregatr_0.5.0.tar.gz |
64.3 KiB |
0.5.0 |
latest linux/noble R-4.5 | segregatr_0.5.0.tar.gz |
64.2 KiB |
0.5.0 |
latest source/ R- | segregatr_0.5.0.tar.gz |
31.2 KiB |
0.5.0 |
2026-04-26 source/ R- | segregatr_0.5.0.tar.gz |
31.2 KiB |
0.5.0 |
2026-04-23 source/ R- | segregatr_0.5.0.tar.gz |
31.2 KiB |
0.5.0 |
2026-04-09 windows/windows R-4.5 | segregatr_0.5.0.zip |
67.6 KiB |
0.4.0 |
2025-04-20 source/ R- | segregatr_0.4.0.tar.gz |
28.9 KiB |