pocrm
Dose Finding in Drug Combination Phase I Trials Using PO-CRM
Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
0.13 |
rolling linux/jammy R-4.5 | pocrm_0.13.tar.gz |
32.8 KiB |
0.13 |
rolling linux/noble R-4.5 | pocrm_0.13.tar.gz |
32.8 KiB |
0.13 |
rolling source/ R- | pocrm_0.13.tar.gz |
5.9 KiB |
0.13 |
latest linux/jammy R-4.5 | pocrm_0.13.tar.gz |
32.8 KiB |
0.13 |
latest linux/noble R-4.5 | pocrm_0.13.tar.gz |
32.8 KiB |
0.13 |
latest source/ R- | pocrm_0.13.tar.gz |
5.9 KiB |
0.13 |
2026-04-26 source/ R- | pocrm_0.13.tar.gz |
5.9 KiB |
0.13 |
2026-04-23 source/ R- | pocrm_0.13.tar.gz |
5.9 KiB |
0.13 |
2026-04-09 windows/windows R-4.5 | pocrm_0.13.zip |
35.2 KiB |
0.13 |
2025-04-20 source/ R- | pocrm_0.13.tar.gz |
5.9 KiB |