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pedgene

Gene-Level Variant Association Tests for Pedigree Data

Gene-level variant association tests with disease status for pedigree data: kernel and burden association statistics.

README

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# rpedgene (pedgene on CRAN)

Gene-level kernel and burden association tests of genetic variants with a trait of interest, allowing for related individuals, including twins.

# Authors

Daniel J. Schaid and Jason P. Sinnwell
Small contribution by A. Visconti

# Manuscript:

[Schaid DJ, McDonnell SK., Sinnwell JP, Thibodeau SN. (2013) **Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data** *Genet Epidemiol*, 37(5):409-18](https://pubmed.ncbi.nlm.nih.gov/23650101/)

Versions across snapshots

VersionRepositoryFileSize
4.1 rolling linux/jammy R-4.5 pedgene_4.1.tar.gz 247.4 KiB
4.1 rolling linux/noble R-4.5 pedgene_4.1.tar.gz 247.4 KiB
4.1 rolling source/ R- pedgene_4.1.tar.gz 247.4 KiB
4.1 latest linux/jammy R-4.5 pedgene_4.1.tar.gz 247.4 KiB
4.1 latest linux/noble R-4.5 pedgene_4.1.tar.gz 247.4 KiB
4.1 latest source/ R- pedgene_4.1.tar.gz 247.4 KiB
4.1 2026-04-26 source/ R- pedgene_4.1.tar.gz 247.4 KiB
4.1 2026-04-23 source/ R- pedgene_4.1.tar.gz 247.4 KiB
3.9 2025-04-20 source/ R- pedgene_3.9.tar.gz 246.4 KiB

Dependencies (latest)

Depends