Crandore Hub

grmsem

Genetic-Relationship-Matrix Structural Equation Modelling (GRMSEM)

Quantitative genetics tool supporting the modelling of multivariate genetic variance structures in quantitative data. It allows fitting different models through multivariate genetic-relationship-matrix (GRM) structural equation modelling (SEM) in unrelated individuals, using a maximum likelihood approach. Specifically, it combines genome-wide genotyping information, as captured by GRMs, with twin-research-based SEM techniques, St Pourcain et al. (2017) <doi:10.1016/j.biopsych.2017.09.020>, Shapland et al. (2020) <doi:10.1101/2020.08.14.251199>.

Versions across snapshots

VersionRepositoryFileSize
1.1.0 rolling source/ R- grmsem_1.1.0.tar.gz 929.6 KiB
1.1.0 rolling linux/jammy R-4.5 grmsem_1.1.0.tar.gz 603.3 KiB
1.1.0 rolling linux/noble R-4.5 grmsem_1.1.0.tar.gz 603.2 KiB
1.1.0 latest source/ R- grmsem_1.1.0.tar.gz 929.6 KiB
1.1.0 latest linux/jammy R-4.5 grmsem_1.1.0.tar.gz 603.3 KiB
1.1.0 latest linux/noble R-4.5 grmsem_1.1.0.tar.gz 603.2 KiB
1.1.0 2026-04-23 source/ R- grmsem_1.1.0.tar.gz 929.6 KiB
1.1.0 2026-04-09 windows/windows R-4.5 grmsem_1.1.0.zip 603.8 KiB
1.1.0 2025-04-20 source/ R- grmsem_1.1.0.tar.gz 929.6 KiB

Dependencies (latest)

Imports

Suggests