gJLS2
A Generalized Joint Location and Scale Framework for Association Testing
An update to the Joint Location-Scale (JLS) testing framework that identifies associated SNPs, gene-sets and pathways with main and/or interaction effects on quantitative traits (Soave et al., 2015; <doi:10.1016/j.ajhg.2015.05.015>). The JLS method simultaneously tests the null hypothesis of equal mean and equal variance across genotypes, by aggregating association evidence from the individual location/mean-only and scale/variance-only tests using Fisher's method. The generalized joint location-scale (gJLS) framework has been developed to deal specifically with sample correlation and group uncertainty (Soave and Sun, 2017; <doi:10.1111/biom.12651>). The current release: gJLS2, include additional functionalities that enable analyses of X-chromosome genotype data through novel methods for location (Chen et al., 2021; <doi:10.1002/gepi.22422>) and scale (Deng et al., 2019; <doi:10.1002/gepi.22247>).
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
0.2.0 |
rolling source/ R- | gJLS2_0.2.0.tar.gz |
124.4 KiB |
0.2.0 |
rolling linux/jammy R-4.5 | gJLS2_0.2.0.tar.gz |
175.2 KiB |
0.2.0 |
rolling linux/noble R-4.5 | gJLS2_0.2.0.tar.gz |
175.1 KiB |
0.2.0 |
latest source/ R- | gJLS2_0.2.0.tar.gz |
124.4 KiB |
0.2.0 |
latest linux/jammy R-4.5 | gJLS2_0.2.0.tar.gz |
175.2 KiB |
0.2.0 |
latest linux/noble R-4.5 | gJLS2_0.2.0.tar.gz |
175.1 KiB |
0.2.0 |
2026-04-23 source/ R- | gJLS2_0.2.0.tar.gz |
124.4 KiB |
0.2.0 |
2026-04-09 windows/windows R-4.5 | gJLS2_0.2.0.zip |
176.4 KiB |
0.2.0 |
2025-04-20 source/ R- | gJLS2_0.2.0.tar.gz |
124.4 KiB |