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famSKATRC

Family Sequence Kernel Association Test for Rare and Common Variants

FamSKAT-RC is a family-based association kernel test for both rare and common variants. This test is general and several special cases are known as other methods: famSKAT, which only focuses on rare variants in family-based data, SKAT, which focuses on rare variants in population-based data (unrelated individuals), and SKAT-RC, which focuses on both rare and common variants in population-based data. When one applies famSKAT-RC and sets the value of phi to 1, famSKAT-RC becomes famSKAT. When one applies famSKAT-RC and set the value of phi to 1 and the kinship matrix to the identity matrix, famSKAT-RC becomes SKAT. When one applies famSKAT-RC and set the kinship matrix (fullkins) to the identity matrix (and phi is not equal to 1), famSKAT-RC becomes SKAT-RC. We also include a small sample synthetic pedigree to demonstrate the method with. For more details see Saad M and Wijsman EM (2014) <doi:10.1002/gepi.21844>.

Versions across snapshots

VersionRepositoryFileSize
1.1.0 rolling source/ R- famSKATRC_1.1.0.tar.gz 11.2 KiB
1.1.0 latest source/ R- famSKATRC_1.1.0.tar.gz 11.2 KiB
1.1.0 2026-04-23 source/ R- famSKATRC_1.1.0.tar.gz 11.2 KiB
1.1.0 2026-04-09 windows/windows R-4.5 famSKATRC_1.1.0.zip 42.4 KiB

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