drmeta

Design-Robust Meta-Analysis via Variance-Function Models

Implements Design-Robust Meta-Analysis (DR-Meta), a variance-function random-effects framework in which between-study heterogeneity is modelled as a function of a study-level design robustness index, allowing heterogeneity to depend systematically on study quality or design strength rather than being treated as a single nuisance parameter. The package provides profiled restricted maximum likelihood (REML) estimation of the overall effect and variance-function parameters, study-specific weights, heterogeneity diagnostics (tau-squared, I-squared), influence and leave-one-out analysis, and graphical tools including forest plots and influence plots. The DR-Meta framework nests classical fixed-effects and standard random-effects meta-analysis as special cases, making it a strict generalisation of existing approaches.

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