Crandore Hub

detectPanel

Leakage-Aware Discovery of Small Biomarker Panels

Discovers small binary-classification biomarker panels from count or expression matrices while prioritizing detectability, expression stability, and univariate discrimination. Candidate filtering and panel selection can be repeated inside nested cross-validation to reduce information leakage. The package provides shared resampling splits, exhaustive small-panel search, logistic model fitting with an automatic ridge fallback for unstable separation-prone fits, out-of-fold evaluation, selection-frequency summaries, and optional 'DESeq2' differential-expression support. The nested model-selection workflow follows Varma and Simon (2006) <doi:10.1186/1471-2105-7-91>, and the optional differential-expression analysis uses Love, Huber, and Anders (2014) <doi:10.1186/s13059-014-0550-8>.

Versions across snapshots

VersionRepositoryFileSize
0.1.3 rolling linux/jammy R-4.5 detectPanel_0.1.3.tar.gz 152.0 KiB
0.1.3 rolling linux/noble R-4.5 detectPanel_0.1.3.tar.gz 151.9 KiB
0.1.3 rolling source/ R- detectPanel_0.1.3.tar.gz 41.4 KiB
0.1.3 latest linux/jammy R-4.5 detectPanel_0.1.3.tar.gz 152.0 KiB
0.1.3 latest linux/noble R-4.5 detectPanel_0.1.3.tar.gz 151.9 KiB
0.1.3 latest source/ R- detectPanel_0.1.3.tar.gz 41.4 KiB
0.1.3 2026-04-23 source/ R- detectPanel_0.1.3.tar.gz 0 B

Dependencies (latest)

Imports

Suggests