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chestR

Kernel-Weighted Cox Regression for Treatment Effect Heterogeneity

Explores treatment effect heterogeneity and candidate predictive biomarkers by re-fitting weighted Cox proportional hazards models on a biomarker grid. Kernel weights centred at each grid point produce local coefficient estimates that can be visualised across biomarker space. Builds on ideas related to graphical Cox treatment-covariate interaction methods [see Bonetti and Gelber (2004) <doi:10.1093/biostatistics/kxh002> and local partial-likelihood approaches Fan, Lin and Zhou (2006) <doi:10.1214/009053605000000796>].

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VersionRepositoryFileSize
0.1.0 rolling linux/jammy R-4.5 chestR_0.1.0.tar.gz 101.4 KiB
0.1.0 rolling linux/noble R-4.5 chestR_0.1.0.tar.gz 101.3 KiB
0.1.0 rolling source/ R- chestR_0.1.0.tar.gz 66.1 KiB
0.1.0 latest linux/jammy R-4.5 chestR_0.1.0.tar.gz 101.4 KiB
0.1.0 latest linux/noble R-4.5 chestR_0.1.0.tar.gz 101.3 KiB
0.1.0 latest source/ R- chestR_0.1.0.tar.gz 66.1 KiB
0.1.0 2026-04-23 source/ R- chestR_0.1.0.tar.gz 0 B

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