POINT
Protein Structure Guided Local Test
Provides an implementation of a rare variant association test that utilizes protein tertiary structure to increase signal and to identify likely causal variants. Performs structure-guided collapsing, which leads to local tests that borrow information from neighboring variants on a protein and that provide association information on a variant-specific level. For details of the implemented method see West, R. M., Lu, W., Rotroff, D. M., Kuenemann, M., Chang, S-M., Wagner M. J., Buse, J. B., Motsinger-Reif, A., Fourches, D., and Tzeng, J-Y. (2019) <doi:10.1371/journal.pcbi.1006722>.
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
1.4 |
rolling linux/jammy R-4.5 | POINT_1.4.tar.gz |
56.4 KiB |
1.4 |
rolling linux/noble R-4.5 | POINT_1.4.tar.gz |
56.3 KiB |
1.4 |
rolling source/ R- | POINT_1.4.tar.gz |
11.3 KiB |
1.4 |
latest linux/jammy R-4.5 | POINT_1.4.tar.gz |
56.4 KiB |
1.4 |
latest linux/noble R-4.5 | POINT_1.4.tar.gz |
56.3 KiB |
1.4 |
latest source/ R- | POINT_1.4.tar.gz |
11.3 KiB |
1.4 |
2026-04-26 source/ R- | POINT_1.4.tar.gz |
11.3 KiB |
1.4 |
2026-04-23 source/ R- | POINT_1.4.tar.gz |
11.3 KiB |
1.4 |
2026-04-09 windows/windows R-4.5 | POINT_1.4.zip |
58.5 KiB |
1.3 |
2025-04-20 source/ R- | POINT_1.3.tar.gz |
10.1 KiB |