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OneArm2stage

Phase II Single-Arm Two-Stage Designs with Time-to-Event Outcomes

Two-stage design for single-arm phase II trials with time-to-event endpoints (e.g., clinical trials on immunotherapies among cancer patients) can be calculated using this package. Two notable advantages of the package: 1) It provides flexible choices from three design methods (optimal, minmax, and admissible), and 2) the power of the design is more accurately calculated using the exact variance in the one-sample log-rank test. The package can be used for 1) planning the sample sizes and other design parameters, and 2) conducting the interim and final analyses for the Go/No-go decisions. More details about the design method can be found in: Wu, J, Chen L, Wei J, Weiss H, Chauhan A. (2020). <doi:10.1002/pst.1983>.

Versions across snapshots

VersionRepositoryFileSize
1.2.1 rolling linux/jammy R-4.5 OneArm2stage_1.2.1.tar.gz 120.5 KiB
1.2.1 rolling linux/noble R-4.5 OneArm2stage_1.2.1.tar.gz 120.4 KiB
1.2.1 rolling source/ R- OneArm2stage_1.2.1.tar.gz 209.6 KiB
1.2.1 latest linux/jammy R-4.5 OneArm2stage_1.2.1.tar.gz 120.5 KiB
1.2.1 latest linux/noble R-4.5 OneArm2stage_1.2.1.tar.gz 120.4 KiB
1.2.1 latest source/ R- OneArm2stage_1.2.1.tar.gz 209.6 KiB
1.2.1 2026-04-26 source/ R- OneArm2stage_1.2.1.tar.gz 209.6 KiB
1.2.1 2026-04-23 source/ R- OneArm2stage_1.2.1.tar.gz 209.6 KiB
1.2.1 2026-04-09 windows/windows R-4.5 OneArm2stage_1.2.1.zip 126.5 KiB
1.2.1 2025-04-20 source/ R- OneArm2stage_1.2.1.tar.gz 209.6 KiB

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