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GSSE

Genotype-Specific Survival Estimation

We propose a fully efficient sieve maximum likelihood method to estimate genotype-specific distribution of time-to-event outcomes under a nonparametric model. We can handle missing genotypes in pedigrees. We estimate the time-dependent hazard ratio between two genetic mutation groups using B-splines, while applying nonparametric maximum likelihood estimation to the reference baseline hazard function. The estimators are calculated via an expectation-maximization algorithm.

Versions across snapshots

VersionRepositoryFileSize
0.1 rolling source/ R- GSSE_0.1.tar.gz 14.2 KiB
0.1 rolling linux/jammy R-4.5 GSSE_0.1.tar.gz 66.8 KiB
0.1 rolling linux/noble R-4.5 GSSE_0.1.tar.gz 66.7 KiB
0.1 latest source/ R- GSSE_0.1.tar.gz 14.2 KiB
0.1 latest linux/jammy R-4.5 GSSE_0.1.tar.gz 66.8 KiB
0.1 latest linux/noble R-4.5 GSSE_0.1.tar.gz 66.7 KiB
0.1 2026-04-23 source/ R- GSSE_0.1.tar.gz 14.2 KiB
0.1 2026-04-09 windows/windows R-4.5 GSSE_0.1.zip 70.0 KiB
0.1 2025-04-20 source/ R- GSSE_0.1.tar.gz 14.2 KiB

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