GMAC
Genomic Mediation Analysis with Adaptive Confounding Adjustment
Performs genomic mediation analysis with adaptive confounding adjustment (GMAC) proposed by Yang et al. (2017) <doi:10.1101/gr.216754.116>. It implements large scale mediation analysis and adaptively selects potential confounding variables to adjust for each mediation test from a pool of candidate confounders. The package is tailored for but not limited to genomic mediation analysis (e.g., cis-gene mediating trans-gene regulation pattern where an eQTL, its cis-linking gene transcript, and its trans-gene transcript play the roles as treatment, mediator and the outcome, respectively), restricting to scenarios with the presence of cis-association (i.e., treatment-mediator association) and random eQTL (i.e., treatment).
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
3.2 |
rolling source/ R- | GMAC_3.2.tar.gz |
270.8 KiB |
3.2 |
rolling linux/jammy R-4.5 | GMAC_3.2.tar.gz |
291.8 KiB |
3.2 |
rolling linux/noble R-4.5 | GMAC_3.2.tar.gz |
291.7 KiB |
3.2 |
latest source/ R- | GMAC_3.2.tar.gz |
270.8 KiB |
3.2 |
latest linux/jammy R-4.5 | GMAC_3.2.tar.gz |
291.8 KiB |
3.2 |
latest linux/noble R-4.5 | GMAC_3.2.tar.gz |
291.7 KiB |
3.2 |
2026-04-23 source/ R- | GMAC_3.2.tar.gz |
270.8 KiB |
3.2 |
2026-04-09 windows/windows R-4.5 | GMAC_3.2.zip |
294.6 KiB |
3.1 |
2025-04-20 source/ R- | GMAC_3.1.tar.gz |
274.3 KiB |