GEVACO
Joint Test of Gene and GxE Interactions via Varying Coefficients
A novel statistical model to detect the joint genetic and dynamic gene-environment (GxE) interaction with continuous traits in genetic association studies. It uses varying-coefficient models to account for different GxE trajectories, regardless whether the relationship is linear or not. The package includes one function, GxEtest(), to test a single genetic variant (e.g., a single nucleotide polymorphism or SNP), and another function, GxEscreen(), to test for a set of genetic variants. The method involves a likelihood ratio test described in Crainiceanu, C. M., and Ruppert, D. (2004) <doi:10.1111/j.1467-9868.2004.00438.x>.
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
1.0.1 |
rolling source/ R- | GEVACO_1.0.1.tar.gz |
189.8 KiB |
1.0.1 |
rolling linux/jammy R-4.5 | GEVACO_1.0.1.tar.gz |
202.3 KiB |
1.0.1 |
latest source/ R- | GEVACO_1.0.1.tar.gz |
189.8 KiB |
1.0.1 |
latest linux/jammy R-4.5 | GEVACO_1.0.1.tar.gz |
202.3 KiB |
1.0.1 |
2026-04-23 source/ R- | GEVACO_1.0.1.tar.gz |
189.8 KiB |
1.0.1 |
2026-04-09 windows/windows R-4.5 | GEVACO_1.0.1.zip |
206.3 KiB |
1.0.1 |
2025-04-20 source/ R- | GEVACO_1.0.1.tar.gz |
189.8 KiB |