DRviaSPCN
Drug Repurposing in Cancer via a Subpathway Crosstalk Network
A systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.
Versions across snapshots
| Version | Repository | File | Size |
|---|---|---|---|
0.1.5 |
rolling linux/jammy R-4.5 | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
rolling linux/noble R-4.5 | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
rolling source/ R- | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
latest linux/jammy R-4.5 | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
latest linux/noble R-4.5 | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
latest source/ R- | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
2026-04-26 source/ R- | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
2026-04-23 source/ R- | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |
0.1.5 |
2025-04-20 source/ R- | DRviaSPCN_0.1.5.tar.gz |
2.4 MiB |